INAPPROPRIATE PRESCRIBING AND ADVERSE DRUG EVENTS IN OLDER PEOPLE

Inappropriate prescribing and adverse drug events in older people

Abstract Inappropriate prescribing (IP) in older patients is highly prevalent and is associated with an increased risk of adverse drug events (ADEs), morbidity, mortality and healthcare utilisation.Consequently, IP is a major safety concern and with changing population demographics, LIQUID B COMPLEX it is likely to become even more prevalent in the

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Triglyceride-Mimetic Prodrugs of Buprenorphine Enhance Oral Bioavailability via Promotion of Lymphatic Transport

Buprenorphine (BUP) is a potent opioid analgesic that is widely used for severe pain management and opioid replacement therapy.The oral bioavailability of BUP, however, is significantly limited by first-pass metabolism.Previous studies have shown that triglyceride (TG) mimetic prodrugs of the steroid hormone testosterone circumvent first-pass metab

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